Hydralazine causes dilation of the walls of blood vessels and is sometimes used to treat hypertension.
Supplementation Likely Helpful
Hydralazine is known to deplete the blood of vitamin B
6. Taking B
6 supplements may prevent or reverse side effects of the medication.1,2
Supplementation Possibly Helpful
There is some evidence that hydralazine might impair the body's ability to manufacture the substance coenzyme Q
This suggests (but definitely does not prove) that taking CoQ
supplements may produce a beneficial effect.
relaxes blood vessels and might have unpredictable effects if combined with hydralazine.
Shils M, et al. (eds.). Modern nutrition in health and disease, 9th ed. Baltimore: Williams and Wilkins, 1999: 1634.
Goodman L and Gilman A. The pharmacological basis of therapeutics, 9th ed. Hardman J, et al (eds.). New York: McGraw-Hill, 1996: 1562.
Kishi H, et al. Bioenergetics in clinical medicine. III. Inhibition of coenzyme Q
-enzymes by clinically used anti-hypertensive drugs.
Res Commun ChemPathol Pharmacol
12(3): 533–40, 1975.
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.