Many antibiotics, including clindamycin, may cause overgrowth of dangerous bacteria in the large intestine. This may cause mild diarrhea or may cause a life-threatening condition called colitis (inflammation of the large intestine). Clindamycin is more likely to cause this type of infection than many other antibiotics, so it should only be used to treat serious infections that cannot be treated by other antibiotics. Tell your doctor if you have or have ever had colitis or other conditions that affect your stomach or intestine.
You may develop these problems during your treatment or up to several months after your treatment has ended. Call your doctor if you experience any of the following symptoms during your treatment with clindamycin injection or during the first several months after your treatment is finished: watery or bloody stools, diarrhea, stomach cramps, or fever.
Talk to your doctor about the risks of receiving clindamycin injection.
WHY is this medicine prescribed?
Clindamycin injection is used to treat certain types of bacterial infections, including infections of the lungs, skin, blood, bones, joints, female reproductive organs, and internal organs. Clindamycin is in a class of medications called lincomycin antibiotics. It works by slowing or stopping the growth of bacteria. Antibiotics such as clindamycin will not kill the viruses that cause colds, flu, and other viral infections.
HOW should this medicine be used?
Clindamycin injection comes as a liquid to be injected intravenously (into a vein) over a period of 10 to 40 minutes or intramuscularly (into a muscle). It is usually given two to four times a day.
You may receive clindamycin injection in a hospital, or you may be given the medication to use at home. If you have been told to use clindamycin injection at home, it is very important that you use the medication exactly as directed. Use clindamycin injection at about the same times every day. Follow the directions that you are given carefully, and ask your doctor, pharmacist, or nurse if you have any questions. Do not use more or less of it or use it more often than prescribed by your doctor.
You should begin to feel better during the first few days of treatment with clindamycin injection. If your symptoms do not improve or if they get worse, call your doctor.
Use clindamycin injection until you finish the prescription, even if you feel better. If you stop using clindamycin injection too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.
Are there OTHER USES for this medicine?
Clindamycin injection is also sometimes used to treat malaria (a serious infection spread by mosquitoes in some parts of the world) and to prevent infection in people who are having certain types of surgery.Clindamycin injection is also sometimes used to treat anthrax (a serious infection that may be spread as part of a bioterror attack) and toxoplasmosis (an infection that may cause serious problems in people who do not have healthy immune systems and in unborn babies whose mothers are infected).
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What SPECIAL PRECAUTIONS should I follow?
Before using clindamycin injection,
- tell your doctor and pharmacist if you are allergic to clindamycin, lincomycin (Lincocin), or any other medications.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention erythromycin (E.E.S, E-Mycin, Erythrocin). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you have or have ever had asthma, allergies, eczema (sensitive skin that often becomes itchy and irritated)colitis (inflammation of the large intestine) or other conditions that affect your stomach or intestines, or liver or kidney disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using clindamycin injection, call your doctor.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are using clindamycin injection.
What SPECIAL DIETARY instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do IF I FORGET to take a dose?
Use the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not use a double dose to make up for a missed one.
What SIDE EFFECTS can this medicine cause?
Clindamycin injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- hardness, pain, or a soft, painful bump in the area where clindamycin was injected
- unpleasant or metallic taste in the mouth
- joint pain
- white patches in the mouth
- thick, white vaginal discharge
- burning, itching, and swelling of the vagina
Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately:
- difficulty breathing or swallowing
- yellowing of the skin or eyes
- decreased urination
Clindamycin injection may cause other side effects. Call your doctor if you have any unusual problems while using this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at Web Site] or by phone [1-800-332-1088].
What should I know about STORAGE and DISPOSAL of this medication?
If you are using clindamycin injection at home, keep the medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
What should I do in case of OVERDOSE?
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
What OTHER INFORMATION should I know?
Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your body's response to clindamycin injection.
Do not let anyone else use your medication. Call your doctor if you still have symptoms of infection after you finish using clindamycin injection.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
AHFS® Consumer Medication Information. © Copyright, The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.
Selected Revisions: February 1, 2009.